| Sanitation 360 | |
| Sarcio AB | |
| SARomics Biostructures AB | |
| Satsuma Studios | |
| Saveggy AB | |
| SaveLend | |
| SAVR AB | |
| Savvy Match | |
| Sawubona IT AB | |
| SBG 18 | |
| SCALINQ | |
| Scandi Group AB | Halland |
| Scandinavian Biopharma | |
| Scandinavian ChemoTech AB | |
| Scandinavian Photo | |
| ScandiNova | |
| ScandiSoft AB | Västra Götaland |
| Scanscot | Skåne |
| Scapin Labs AB | |
| Schoolido AB | |
| SchoolSoft | |
| Sci-Hub | |
| SciBase Holding AB | |
| ScientificMed Tech AB | |
| SciFree AB | |
| SciTech Software AB | Stockholm |
| Scoreit AB | Skåne |
| Scotten Scotten WebbDesign & Sökmotoroptimering | Stockholm |
| SCRIIN | |
| Scrintal | |
| Scrive | Stockholm |
| SDC Automation AB | |
| Sdiptech AB | |
| SDS Life Science | |
| SDT | |
| Seamless Distribution Systems | |
| Seaqure Labs AB | |
| Seaqure Labs AB | |
| Search Integration | Skåne |
| Searchminds Group | |
| Seavus | Skåne |
| Sectra AB | Östergötland |
| Securifid | |
| Sedana Medical AB | |
| Seesecure | |
| Sekurbit Sverige AB | |
| Selfcheck AB | |
| Selfpoint Sverige AB | |
| Sellhelp AB | |
| Semio | Stockholm |