| Infusionz Design | Singapore |
| Ink and Pixel Pte Ltd | Singapore |
| InMobi | |
| Innogene Kalbiotech | |
| InnoMedia | Singapore |
| Innomedia Technologies Pte Ltd | Singapore |
| Innopartner Pte Ltd | |
| Innoport Pte Ltd | Singapore |
| Innotel Solutions | Singapore |
| Innovate 360 Pte Ltd | Singapore |
| Innovax Systems | Singapore |
| InnoVen Capital | Singapore |
| Innovez-one.com | Singapore |
| Ino Mobile (Singapore) Pte Ltd | Singapore |
| Inok Systems | Singapore |
| iNova Pharmaceuticals | |
| Inshorts Pte Ltd | |
| InsiderSecurity | Singapore |
| Insignia Ventures Partners | Singapore |
| Insphere Technology Pte Ltd | Singapore |
| Inspius Singapore Pte Ltd | |
| Institute of Technical Education | Singapore |
| Insync | Singapore |
| Integral Solutions (Asia) Pte Ltd | Singapore |
| Integratech Pte Ltd | Singapore |
| Integrated Retail | Singapore |
| Integrated Software Engineering Pte Ltd | Singapore |
| Integro Technologies Pte Ltd | Singapore |
| Intellisoft Systems | Singapore |
| Intensecomp | Singapore |
| InteractiveMedia AD | Singapore |
| International Centre For Thoracic Surgery | |
| International Journal of Computer Theory and Engineering | |
| International Payments Identity (iPiD) Pte Ltd | Singapore |
| International Technology System | Singapore |
| interTouch Pte Ltd | Singapore |
| Interviewer.AI Pte Ltd | Singapore |
| Intrepid Group Asia | Singapore |
| Intrinix Networks Pte Ltd | Singapore |
| Invitrocue | Singapore |
| IOHK | Singapore |
| IoTeX | Singapore |
| IP Mirror | Singapore |
| iPanel Pte Ltd | Singapore |
| ipaymy | Singapore |
| IPC Corporation Ltd | Singapore |
| iPhonefix | Singapore |
| iPixel Creative | Singapore |
| iqDynamics Pte Ltd | Singapore |
| Isage Communications Pte Ltd | Singapore |