| EdgeWorks | Singapore |
| Edlution Pte Ltd | Singapore |
| EDMI Ltd | Singapore |
| Ednovation Pte Ltd | Singapore |
| EDPR Sunseap | Singapore |
| EduSpaze Pte Ltd | Singapore |
| Effective Gadgets | Singapore |
| eFusion Technology Pte Ltd | Singapore |
| EGIS Healthcare Technologies Pte Ltd | Singapore |
| EI-Infocomm Pte Ltd | Singapore |
| Ekipa Consultancy Pte Ltd | Singapore |
| Ekipa Consultancy Pte Ltd | |
| Elec & Eltek International Company Ltd | Singapore |
| Elecom Marketing Pte Ltd | Singapore |
| Electronic Art & Design | Singapore |
| Electrotek Pvt Ltd | Singapore |
| Elemaths Software | Singapore |
| Elevan August Media | Singapore |
| Elixir Technology | Singapore |
| Ellipsiz Ltd | Singapore |
| Elms Industrial Pte Ltd | Singapore |
| Elves Lab Pte Ltd | Singapore |
| Ematic Solutions Pte Ltd | Singapore |
| Emeritus | |
| EmiNET Pte Ltd | Singapore |
| Emurgo Pte Ltd | Singapore |
| Enable Computing | Singapore |
| EnableX | Singapore |
| Encore eServices | Singapore |
| Energeia Labs Pte Ltd | Singapore |
| Engine Biosciences Pte Ltd | Singapore |
| Enjin | Singapore |
| Enjinstarter | |
| Enleofen Bio Pte Ltd | Singapore |
| Ennovatez Group | Singapore |
| eNova Technologies Pte Ltd | Singapore |
| Enspire Capital Pte Ltd | Singapore |
| Enterprise Products Integration Pte Ltd | Singapore |
| Enterprise Singapore | Singapore |
| Entropica Labs | Singapore |
| Entrust Network | Singapore |
| Eoan Systems | Singapore |
| Epecom Graphics | Singapore |
| EPLAN Software & Service | Singapore |
| Epoint Systems Pte LTd | Singapore |
| ePrime Solutions Pte Ltd | Singapore |
| EPS Ventures | Singapore |
| Epson Singapore Pte Ltd | Singapore |
| Equatorial Space Systems Pte Ltd | Singapore |
| Equinet Academy | Singapore |