| Ruminant BioTech | |
| Rush | Auckland |
| RWB | Auckland |
| Ryze | Auckland |
| SaaS Digital | |
| Safemode | |
| SaferMe Ltd | Wellington |
| SafeStack | |
| Sahha | |
| Sales App Centre Ltd | Auckland |
| Sales Magnet Ltd | |
| Salt Design | Auckland |
| Sam Jarman | |
| Sandbox | Wellington |
| Sandfield | Auckland |
| Sandfly Security Ltd | |
| Scale-Up New Zealand | Auckland |
| Scarabaeus Ltd | Bay of Plenty |
| Sccop - Sci-Tech | Auckland |
| Scentian Bio | |
| Schurg IT-Solutions | Otago |
| Scope IT | |
| Scott Technology | |
| Scottronic Technologies 2001 Ltd | Northland |
| Sea Air and Land Communications Ltd | Canterbury |
| Seabreeze Software | Auckland |
| Seamless Webtools | Auckland |
| SearchMasters 2015 Ltd | Manawatu-Wanganui |
| Searle Electronics | Northland |
| Second Mile Internet Solutions | Bay of Plenty |
| SecOps | Auckland |
| See Tomorrow First | |
| SeedSpider | |
| Seekom | Wellington |
| SeeMee Media | |
| Seequent | Canterbury |
| Sektor Ltd | Auckland |
| Sentient Software Ltd | Auckland |
| SEO Pros | |
| SEOPro NZ Ltd | Auckland |
| Serko Ltd | Auckland |
| Serrata Systems & Software Ltd | Auckland |
| Service Dynamics | |
| Service Plus Group Ltd | Auckland |
| Setpoint Solutions Ltd | |
| Seven Day AI | |
| SeventyTwo | Auckland |
| SF Web Services | |
| ShadowTech | |
| SharedPod | Wellington |