| Digital Guru | Johor |
| Digital Nasional Berhad | |
| Digital News Asia Sdn Bhd | Kuala Lumpur |
| Digital Omnis Consulting Sdn Bhd | |
| Digital Primate | Kuala Lumpur |
| DIKA College | |
| DoMedia Asia Sdn Bhd | |
| Dong Jiao Higher Learning Centre Bhd | |
| Dot Effect Technology | Selangor |
| DPI Technology Sdn Bhd | Kuala Lumpur |
| DRB-HICOM University of Automotive Malaysia | |
| Dreamztech (M) Berhad | Johor |
| DSH Institute of Technology | |
| Duopharma Biotech Berhad | |
| DynaFront Holdings Berhad | Kuala Lumpur |
| E Venture Design Enterprise | Selangor |
| e-Lock Corporation Sdn Bhd | Kuala Lumpur |
| e-Marketing Malaysia | Selangor |
| e-pay (M) Sdn Bhd | Selangor |
| E-Solutions Technology Sdn Bhd | Selangor |
| EA-Link System Bhd Sdn | Selangor |
| East West International College Sdn Bhd | |
| Easy Asia Technologies Sdn Bhd | |
| Easy Asia Technologies Sdn Bhd | |
| Easy UI Software | Kuala Lumpur |
| EasyNet Interactive | Kuala Lumpur |
| EasyStore Commerce Sdn Bhd | Selangor |
| EasyUni Sdn Bhd | Selangor |
| EBTech | |
| Ecompile | |
| Edense Sdn Bhd | |
| Edex Technology Sdn Bhd | Selangor |
| EDMS Consultants | Selangor |
| Egenz.com | Kuala Lumpur |
| Eko Solution | Penang |
| Ektech Holdings Sdn Bhd | Selangor |
| Elabram Group | |
| eLifeStyles | |
| Elite Web Solutions | Kuala Lumpur |
| Elliance System Sdn Bhd | Penang |
| Emanon | Penang |
| EnterpriseBuilder | Selangor |
| Entomo Malaysia Sdn Bhd | |
| Envigeek | |
| eOneNet.com Sdn Bhd | Kuala Lumpur |
| Equator College | |
| Erican Language Centre | |
| Ericanfly.com | Selangor |
| eSolutions Webbers | Kuala Lumpur |
| eSolved MSC Sdn Bhd | Penang |