| SENTRAL College Penang | |
| Serba Dinamik Sdn Bhd | |
| Sherman3D Sdn Bhd | |
| Shinjiru International, Inc. | Kuala Lumpur |
| Shinjiru Technology Sdn Bhd | Kuala Lumpur |
| Shock Media Studio | Selangor |
| Shoppego Sdn Bhd | |
| Shoppertise Sdn Bhd | Kuala Lumpur |
| Shortcut Asia Sdn Bhd | |
| SIDMA College | |
| SigMax-e | Selangor |
| Silentmode Sdn Bhd | |
| Siliconnet Technologies Sdn Bhd | Sarawak |
| Silterra Malaysia Sdn Bhd | Kuala Lumpur |
| Silver Circuits Sdn Bhd | Selangor |
| Silverlake Axis Ltd | Selangor |
| Simon Systems | Kuala Lumpur |
| Simple Internet Communications Sdn Bhd | |
| Simplify | Kuala Lumpur |
| SIRIM Berhad | |
| SkyeChip Sdn Bhd | |
| Skytomato Sdn Bhd | Selangor |
| SMART College | |
| SmartLab Sdn Bhd | Penang |
| Snappymob | Kuala Lumpur |
| Soft Space Sdn Bhd | Kuala Lumpur |
| Softdiv Software | Penang |
| SoftDomain Systems | Kuala Lumpur |
| Softinn Solutions Sdn Bhd | Malacca |
| Softkey E-Solution Sdn Bhd | Selangor |
| Solaris IT Solutions | |
| Southern University College | |
| Southpaw Sdn Bhd | |
| Spanlogic Solution Sdn Bhd | Penang |
| Specflux Solutions | |
| Spectrum Holdings | |
| Spider Asia Sdn Bhd | Selangor |
| SpurPress | |
| SRI College | |
| Sri Komputer Sdn Bhd | Sabah |
| SRM Integration (M) Sdn Bhd | Penang |
| Stack Ideas Sdn Bhd | Kuala Lumpur |
| Stamford College | |
| START Malaysia | Kuala Lumpur |
| Startup Malaysia | Kuala Lumpur |
| Stelix Media | |
| STI College Malaysia | |
| StoreHub | Selangor |
| Stradford College | |
| Streamline Media Group, Inc. | Kuala Lumpur |