| La Tecnika Due S.r.l. | Turin |
| LAB Creative Thinking | Milan |
| Lab Evo S.r.l. | |
| Lab011 | Turin |
| LABEL S.r.l. | |
| Labex S.r.l. | Pavia |
| Labitech S.r.l. | Parma |
| Labospace | |
| Labso Informatica S.r.l. | Monza and Brianza |
| LAE Electronic S.r.l. | Treviso |
| Laila | Caserta |
| Lake Web S.r.l. | Verbano-Cusio-Ossola |
| LAM Technologies | |
| Lameplast S.r.l. | |
| Lan & Wan Solutions S.r.l. | Padua |
| Lan Service S.r.l. | Alessandria |
| Lan Systems S.r.l. | |
| LanMan Group | Milan |
| Laser S.r.l. | Modena |
| Lasting Dynamics | |
| Lateral S.r.l. | |
| Latina Linux User Group | Latina |
| Latitudo 40 | Naples |
| Lauretti Automazioni Industriali | Frosinone |
| Layer Electronics S.r.l. | Trapani |
| Layoutweb | Milan |
| LB Research S.r.l. | |
| LCR Elettronica S.r.l. | Milan |
| Lead Discovery Siena S.r.l. | |
| Lead S.r.l. | Varese |
| Leader | Trento |
| Leaf Space | Como |
| Léally S.r.l. | |
| Lean Solutions S.r.l. | |
| Leanus | Milan |
| Lecit Consulting | Pisa |
| LECS | Ascoli Piceno |
| Led Electronics | Bologna |
| LemonWeb | Agrigento |
| Lena S.a.s. | Venice |
| Lenus Media | Salerno |
| Leomatic S.r.l. | Bologna |
| Leonardo Interactive S.r.l. | |
| Leonardo S.p.A. | Rome |
| Leonardo Software House S.r.l. | Cagliari |
| Leva | |
| LexDo.it S.r.l. | |
| Lexroom S.r.l. | |
| Liablix S.r.l. | |
| Libellula S.r.l. | Cuneo |