| RDC Informatics | |
| Real Consulting | |
| Reboot bots | Attica |
| Redirect | Attica |
| Redtie Digital | |
| Regate A.E. | Attica |
| Relational S.A. | Attica |
| René Descartes College | |
| ResQ Biotech | |
| Ristart | Central Macedonia |
| Rocket Path | |
| Rodos Web Design | |
| Sally | |
| Sapce Hellas | |
| Saravanos S.A. | |
| ScaleApp | |
| School of Informatics of AUTh | Central Macedonia |
| Science and Technology park of Crete | Crete |
| Scientia Maris | Attica |
| SciFY | |
| SDM | Attica |
| Seapixel | |
| Search Engine Marketing Greece | Attica |
| Sekee | Attica |
| Semantic Business Software | |
| SEO Dominator | Attica |
| Seo Future | Attica |
| Seradis | Attica |
| Shop13 | Attica |
| Sieline A.E. | |
| Sigma Hellas Ltd | |
| Sigmasoft | Central Macedonia |
| Simple Firm, Inc. | Attica |
| SimpleApps | |
| SingularLogic | Attica |
| SingularLogic | |
| SinisGroup | |
| SKGTech | |
| Skroutz.gr | |
| Sleed | |
| SLT Samaras | |
| Smart Kit Electronics | Attica |
| Smart NS | Attica |
| Smart Systems A.E. | |
| Smartec S.A. | |
| SmartVision | Attica |
| SMS.gr | Attica |
| SMS.net.gr | Attica |
| Snn.gr | Attica |
| Social Mind | Attica |