| Center Centre, Inc. | Massachusetts |
| Center for Advanced Self-Powered Systems of Integrated Sensors and Technologies | North Carolina |
| Center for Advancing Retail & Technology | |
| Center for American Entrepreneurship | District of Columbia |
| Center for Automotive Embedded Systems Security | |
| Center for Automotive Research | Michigan |
| Center For Black Innovation | |
| Center for Breakthrough Medicines | Pennsylvania |
| Center for Democracy & Technology | District of Columbia |
| Center for Diagnostic Imaging | Minnesota |
| Center for Economic and Policy Research | |
| Center for Information Management, Inc. | Michigan |
| Center for Innovative Technology | Virginia |
| Center for Internet Security | New York |
| Center for Neurologic Study | |
| Center for Professional Innovation and Education, Inc. | Pennsylvania |
| Center for Quantum Networks | Arizona |
| Center for Space Commerce and Finance | |
| Center for Strategic & International Studies | |
| Center for the Collaborative Classroom | |
| Center Key | California |
| Center of Financial Technologies, Inc. | Illinois |
| Center State Software | California |
| Centerbase | Texas |
| Centercode | California |
| CenterEdge Software | North Carolina |
| Centerfield | |
| Centerfire Antenna, LLC | Indiana |
| Centeris | Washington |
| Centerline Biomedical | Ohio |
| Centerline Communications, LLC | Massachusetts |
| Centerline Software | Texas |
| Centerlogic, Inc. | Washington |
| Centerprise Services | New York |
| Centers for Applied Competitive Technologies | California |
| CenterSpace Software | Oregon |
| CenTex Printing, Inc. | |
| Centime, Inc. | Massachusetts |
| Centinel Spine, LLC | Pennsylvania |
| Centium Consulting, Inc. | Massachusetts |
| Centium Software | Washington |
| Centivax | California |
| Centivo | |
| Centon Electronics | California |
| Centona Corporation | California |
| Centrada Solutions, LLC | Texas |
| CenTrak | Pennsylvania |
| Central Arizona College | Arizona |
| Central Arkansas Telephone Cooperative | Arkansas |
| Central Baptist College | Arkansas |