| Cajun tech | Wyoming |
| Cake | |
| Cake AI Technologies, Inc. | |
| Cake Development Corporation | |
| Cake Farm | California |
| CakeBoss | Texas |
| CakePHP | Nevada |
| Caktus | North Carolina |
| Cal Poly State University Computer Engineering | California |
| Cal Quality Electronics | California |
| Cal-AV Labs, Inc. | Arizona |
| Cal-Impact Accellerator | California |
| Cal.com, Inc. | |
| Cal.net, Inc. | California |
| CALA | New York |
| Cala Health | California |
| Calabrio, Inc. | Minnesota |
| Caladan Bio | |
| CalAmp | California |
| Calance | California |
| Calavista Software | Texas |
| CalBiotech | California |
| Calbright College | California |
| Calcguard Technologies, LLC | Illinois |
| CalChem Synthesis, Inc. | California |
| Calchemy Software, Inc. | Colorado |
| CalciMedica | California |
| Calcium | New York |
| Calcium Health | |
| Calcivis, Inc. | Massachusetts |
| Calculators, Inc. | Maryland |
| Calculus In Motion | California |
| Calculus.org | California |
| CalcuQuote | Texas |
| Calder Biosciences, Inc. | New York |
| Calder Solutions, Inc. | |
| Caldera | |
| Caldera Medical | California |
| Caldiatech | California |
| Caldwell Computer Consulting | North Carolina |
| Caldwell University | New Jersey |
| Caleidoscope Communications | Vermont |
| Calendar Updates, LLC | Oregon |
| Calendar, Inc. | Utah |
| Calendarific | California |
| Calendly | Georgia |
| Calero | New York |
| Calero-MDSL | New York |
| CalGreg Electronics, Inc. | Rhode Island |
| Calhoun Technologies | Minnesota |