| Bubbles | California |
| BubbleUp, LLC | |
| Bublitz Creative | Wisconsin |
| Bucey Software | |
| Buchanan & Edwards | Virginia |
| Buchanan Technologies | Texas |
| BUCK | California |
| Buckard Design, Inc. | |
| Buckeye CableSystem | Pennsylvania |
| Buckeye Shapeform | Ohio |
| Buckhead Business Consulting Management and Marketing, LLC | Georgia |
| Bucknell University | Pennsylvania |
| Bucknell University Computer Science | Pennsylvania |
| BucksApp | Florida |
| BUCS Analytics | Missouri |
| Buda Consulting, Inc. | New Jersey |
| Buddha SEO | |
| Buddipole, Inc. | Oregon |
| Buddy Punch | |
| Buddy Web Design & Development | |
| Buderflys Technologies, Inc. | |
| Budget Digital Solutions, LLC | |
| BUDGET Document Technology | Maine |
| Budgetpulse | Virginia |
| Buena Vista University | Iowa |
| Buenavista | |
| Buffalo Americas, Inc. | Texas |
| Buffalo Automation Group | New York |
| Buffalo Power Electronics Center, Inc. | New York |
| Buffalo State University | New York |
| Buffalo Web Services, LLC | New York |
| Buffer | California |
| Buford Advertising, Inc. | |
| Bug Labs, Inc. | |
| Bugaboo Software | Wisconsin |
| Bugcrowd, Inc. | California |
| BugentaiTech | Arizona |
| Bugeye Technologies, Inc. | Missouri |
| BugHost | Oregon |
| BugRaptors | California |
| Bugsee, Inc. | |
| BugsIO Solutions | Michigan |
| Bugsnag, Inc. | California |
| BugSplat | New Hampshire |
| BUGtrack | Illinois |
| Bugzilla | |
| BUHLMANN Diagnostics Corporation | |
| Build Better App | |
| Build Capital Partners, LLC | Utah |
| Build412 Tech | |