| BigHat Biosciences | California |
| Bighorn Design | Wyoming |
| Bighorn Web Solutions, LLC | |
| BigHosts.com | Florida |
| Bighouse Marketing | North Carolina |
| Bigleaf Networks, Inc. | |
| BigLever Software, Inc. | Texas |
| BIGLIST, Inc. | Pennsylvania |
| BigLook360 | Texas |
| BigML, Inc. | Oregon |
| BigMove Agency | |
| BigPanda | California |
| BigRio, LLC | |
| Bigscreen, Inc. | |
| BigShort, Inc. | |
| BigSIS | Colorado |
| BigsmallWeb | Illinois |
| Bigsquid, Inc. | Utah |
| Bigstep, Inc. | Illinois |
| BigThumb | Ohio |
| BigTime Software, Inc. | Illinois |
| Bigtincan | Massachusetts |
| BigWave Software, LLC | Texas |
| bigWebApps, Inc. | Georgia |
| BigWheel | Tennessee |
| biix | California |
| Bike Shop SEO | Colorado |
| Bilberry | Washington |
| Bildr | Texas |
| Bilectron, Inc. | Pennsylvania |
| Bill Nye | |
| Bill.com, Inc. | California |
| bill4Time | Washington |
| Billables, Inc. | |
| BillboardPlanet, LLC | Minnesota |
| Billd, LLC | Texas |
| Billed | Texas |
| Biller Genie | Florida |
| Billfire, LLC | Arizona |
| BillFlash | |
| Billforward | California |
| BillGO, Inc. | Colorado |
| BillingOrchard | Ohio |
| BillingPlatform | Colorado |
| Billion Hosting | |
| Billionapps Infotech Solutions | |
| Billions in Change, LLC | |
| BillionToOne, Inc. | California |
| BillionToOne, Inc. | |
| Billnet Solutions | Florida |