| B2 Web Studios | Wisconsin |
| B2B Cloud Solutions | Florida |
| b2b Commerce, LLC | |
| B2B Rocket | |
| B2B Soft | New York |
| B2B Technologies, LLC | Georgia |
| B2E Direct Marketing, Inc. | Iowa |
| b2evolution | California |
| B2Gnow | Arizona |
| B2i Technologies | |
| B2i Technologies, Inc. | Texas |
| B2S Life Sciences | Indiana |
| B2W Software, Inc. | New Hampshire |
| B37 Ventures | California |
| B3NET, Inc. | California |
| B4Computers | New York |
| B612 Foundation | |
| B::Ware | New Jersey |
| B@kerBytes | Alabama |
| BA Insight | New York |
| BA Sciences | New Hampshire |
| Baal & Spots, LLC | |
| BAAM.Tech | Kansas |
| Babbage & Turing | |
| Babbage Simmel | Ohio |
| Babson College | Massachusetts |
| Babson Diagnostics | Texas |
| Babson Diagnostics, Inc. | |
| Baby Steps | California |
| BabyGroot | |
| Babylon Labs | |
| Babyscripts | District of Columbia |
| BabySentry | California |
| Bach Pharma, Inc. | |
| Bachman Brand Development | |
| Báchoo | |
| Back At You | |
| Back Bay Accounting Software Consultants, Inc. | New York |
| Back Bay Large Installation System Administration | Massachusetts |
| Back Thru The Future Technology Disposal | New Jersey |
| Back To Back SWE | |
| Back2Black Agency | |
| Back40 Design Group | Oklahoma |
| Back4App, Inc. | California |
| Backbase | California |
| BackBay Networks | New Hampshire |
| BackBlaze, Inc. | California |
| Backbone Media, Inc. | Massachusetts |
| Backbone PLM | Colorado |
| Backbone Security | Massachusetts |