| SuperAnnotate | California |
| SuperAnnotate AI, Inc. | |
| SUPERAntiSpyware | California |
| SuperAtic, Inc. | |
| Superba | |
| SuperBeings | Delaware |
| Superblocks | New York |
| Supercede Therapeutics, Inc. | |
| Supercircuits, Inc. | Texas |
| Superclean Web Services | California |
| Supercomputing Challenge | New Mexico |
| Supercreator.ai | New York |
| SuperData Research Holdings, Inc. | |
| Superdigital | |
| Superfeedr | California |
| Superflow | California |
| Superfluid Dx, Inc. | California |
| Superfly | |
| Supergrain | California |
| SuperHero IT Solutions | |
| Superhuman | California |
| Superintelligent AI | |
| Superior Automation | California |
| Superior BioDiagnostics | |
| Superior Communication Services | |
| Superior Computers | Utah |
| Superior Consulting Services | Minnesota |
| Superior Essex, Inc. | Georgia |
| Superior IT Services, Inc. | Minnesota |
| Superior Resources, Inc. | California |
| Superior Solutions, Inc. | Texas |
| Superlative | California |
| Superlative Internet | Washington |
| Superlative Systems Integration, Inc. | New York |
| Superlative, Inc. | California |
| Superlink Technology | California |
| Superlinked | |
| Superluminal Medicines, Inc. | Massachusetts |
| Superluminal Medicines, Inc. | |
| Supermassive Studios | Wisconsin |
| Supermaven, Inc. | |
| Supermoon Labs, Inc. | South Carolina |
| Supermove | California |
| Supernormal Technologies, Inc. | |
| Supernormal Technologies, Inc. | New York |
| Supernova Games | Wyoming |
| Supernova.io, Inc. | Delaware |
| Supernus Pharmaceuticals, Inc. | |
| SuperOps | |
| SuperOps.ai | Delaware |