| South Coast Computers | California |
| South College | North Carolina |
| South Com Data, Inc. | Georgia |
| South Dakota Mines Electrical Engineering and Computer Science | South Dakota |
| South Dakota State University McComish Department of Electrical Engineering and Computer Science | South Dakota |
| South Florida ColdFusion Users Group | Florida |
| South Florida IT Staffing | |
| South Florida PC Repair | Florida |
| South Florida State College | Florida |
| South Fork Technologies, Inc. | Washington |
| South Georgia State College | Georgia |
| South Georgia Technical College | Georgia |
| South Hills School of Business & Technology | Pennsylvania |
| South Jersey SEO | New Jersey |
| South Jersey Techies, LLC | New Jersey |
| South Jersey Web Design | |
| South Lake Computers | |
| South Patron, LLC | Wyoming |
| South Plains College | Texas |
| South Rampart Pharma, Inc. | |
| South Reach Networks | |
| South River Technologies | Maryland |
| South Seas Data, LLC | Colorado |
| South Seattle College | Washington |
| South Shore Digital Marketing | |
| South Street & Co. | |
| South Suburban College | Illinois |
| South Target | |
| South Texas College | Texas |
| South University | Georgia |
| South Ventures, LLC | Oregon |
| South Western Communications, Inc. | Indiana |
| South-Pak, Inc. | |
| Southcentral Foundation | |
| Southcentral Kentucky Community & Technical College | Kentucky |
| SouthData, Inc. | North Carolina |
| Southeast Arkansas College | Arkansas |
| Southeast Computer Solutions | Florida |
| SouthEast Controls, Inc. | Georgia |
| Southeast Kentucky Community and Technical College | Kentucky |
| Southeast Laser, Inc. | Georgia |
| SouthEast LinuxFest | North Carolina |
| Southeast Media, Inc. | |
| Southeast Missouri State University | Missouri |
| SouthEast SAS Users Group | Virginia |
| Southeast Solutions, Inc. | Georgia |
| Southeast TechInventures, Inc. | North Carolina |
| Southeast Technical College | South Dakota |
| Southeast Valley .NET User Group | Arizona |
| Southeastern Baptist College | Mississippi |