| Olbo | |
| Omega Telecom | Larnaca |
| Omilia Natural Language Solutions Ltd | Larnaca |
| Onelight Apps | |
| Open University of Cyprus | Nicosia |
| Oracle Studios | |
| Owlcat Games | Paphos |
| Oxxy S.A. | Nicosia |
| PA College | |
| Pale Blue Software Ltd | |
| Paradigma Sports Tech | |
| Payboard Network | |
| PDF Guru | |
| Perpetual Biotechnologies Ltd | Nicosia |
| Philips College | |
| Pingle Studio Ltd | |
| Pittas & Valerkos Software Ltd | Nicosia |
| Polarity Technologies Ltd | Nicosia |
| Postgraduate Research Institute of Science, Technology, Environment and Medicine | |
| Powersoft Computer Solutions Ltd | Nicosia |
| Powersoft Ltd | Nicosia |
| Prestigio Plaza | Limassol |
| Prime Web Solutions | Paphos |
| PrimeTel plc | Limassol |
| Prisma Computer Ltd | Nicosia |
| Probanx Solutions Ltd | Nicosia |
| Progressive Technologies | Limassol |
| Promed Bioscience | Limassol |
| Promova | |
| Pynest | |
| Qualiteam Software Ltd | Limassol |
| Qumaron | Nicosia |
| R Digital Agency | Nicosia |
| Radius Fintech | Limassol |
| Recorn Ltd | Nicosia |
| Regtify Ltd | Nicosia |
| Remedica Ltd | Limassol |
| Renaissance Securities (Cyprus) Ltd | |
| Research & Innovation Foundation | Nicosia |
| RJ Games Ltd | Limassol |
| Ruxbo Ltd | |
| S.S. Netshop Internet Services Ltd | Larnaca |
| Sad Cat Studios Ltd | Limassol |
| SafetyBis.com | |
| San Vaneco Online Web Shop | Nicosia |
| Sednor Holdings Ltd | |
| SEOServices.com | |
| Setapp | |
| Simplex | Limassol |
| Singular Computers Systems Ltd | Limassol |