| Inovatec | |
| Inovestor, Inc. | Quebec |
| Inovex, Inc. | Ontario |
| Inovia Capital | Quebec |
| Inovision | Quebec |
| InPilot Technologies | |
| Input Logic, Inc. | British Columbia |
| InputKit | |
| Inquim International, Inc. | |
| Inquiry Management Systems, Inc. | |
| INRO | Quebec |
| inRound Innovators | Ontario |
| INSA Corporation | Ontario |
| Insertech | Quebec |
| InServio | Quebec |
| Inside Mac Games Ltd | Alberta |
| Insight as a Service | Ontario |
| Insight Medbotics | |
| Insight Medical | |
| InsightStudio | Prince Edward Island |
| Insighty | Ontario |
| Insign IT | British Columbia |
| Insignia Software | |
| Insignis Design, Inc. | Ontario |
| InSite Creations | Ontario |
| Insiteful Solutions | Ontario |
| inSites Creative | Ontario |
| Insix, Inc. | Ontario |
| InspectAR | Newfoundland and Labrador |
| Inspecto, Inc. | |
| Inspiratica Web Services | Ontario |
| Inspiration Design | New Brunswick |
| Inspired Networks | British Columbia |
| Inspired Robotics | |
| Inspired Telecom | Ontario |
| InspiredElectrons | British Columbia |
| Inspyder Software, Inc. | Ontario |
| Insta Software | |
| Instacable | Quebec |
| Instadesign | Quebec |
| Instalogic Marketing | |
| Instant Housecall | Ontario |
| Instant Solutions Technical Services | Ontario |
| Instappraise, Inc. | |
| Instech Télécommunication | Quebec |
| Instil Math Science | |
| Institut bioalimentaire estrien | |
| Institut de Cardiologie de Montréal | |
| Institut de recherche Robert-Sauvé en santé et en sécurité du travail | |
| Institut de recherches cliniques de Montréal | |