| Focality Interactive | Ontario |
| FOCUS by TELUS | |
| Focus College | |
| Focus computers | Ontario |
| Focus FS | |
| Focus IT Solutions | British Columbia |
| Focus Print Production | Ontario |
| Focus Telecom | Quebec |
| Focus21 | |
| Foilmedia | Ontario |
| FOIP Software | British Columbia |
| FOLKS | |
| Fondaction | |
| Fonds de recherche du Québec | |
| Fonds de solidarité FTQ | |
| Fonds Ecofuel | |
| Fonds Émergence Estrie | |
| Fonemed | |
| FONEX data systems, Inc. | Quebec |
| Fontech Solutions, Inc. | |
| Food Decision Software, Inc. | Ontario |
| Food For Thought Software Solutions | Nova Scotia |
| Food Island Partnership | |
| Foodage | |
| Footeprint | British Columbia |
| Foqus Technologies, Inc. | |
| Forbes IT | |
| Forbius | Quebec |
| Force 5, Inc. | Quebec |
| Force Five Media | Ontario |
| Force T.I. | Quebec |
| Forensic Notes | |
| Forensic Technology WAI, Inc. | Quebec |
| Foresee Computing, Inc. | Ontario |
| Foresight CAC | British Columbia |
| Foresight for IT | Alberta |
| Forest Communications | Ontario |
| Forest Computers | Manitoba |
| ForestCityWebDesign | |
| Forestry.io | Prince Edward Island |
| ForeTell Technologies Ltd | Manitoba |
| Forge and Smith | |
| Forge Media | Ontario |
| Forges Media | |
| Forgestik, Inc. | Quebec |
| ForInsite | Ontario |
| Form & Affect, Inc. | Ontario |
| Form Innovation, Inc. | Ontario |
| Form:Media | Nova Scotia |
| Forma.ai | |